DEPOT MEDROXYPROGESTERONE ACETATE (DMPA) ENHANCES SUSCEPTIBILITY AND INCREASES THE WINDOW OF VULNERABILITY TO HIV-1 IN HUMANIZED MICE

Depot medroxyprogesterone acetate (DMPA) enhances susceptibility and increases the window of vulnerability to HIV-1 in humanized mice

Abstract The progestin-based hormonal contraceptive Depot Medroxyprogesterone Acetate (DMPA) is widely used in sub-Saharan Africa, where HIV-1 is endemic.Meta-analyses have shown that women using DMPA are 40% more likely than women not using hormonal contraceptives to acquire Human Immunodeficiency Virus (HIV-1).Therefore understanding how DMPA inc

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PARAMETERS OF THE INFLUENCE OF THE POLITICAL CENTER OF RUSSIA ON THE OUTLYING TERRITORIES IN THE IMPERIAL PERIOD

The article discusses the ways and mechanisms of the influence of the political center zilla water conditioner of the empire on the imperial outskirts.A feature of the imperial administrative system in Russia was its absolutist character.For this reason, all existing imperial state bodies that had the right to rule-making carried out delegated rule

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Sentinel node biopsy using blue dye and technetium99 in advanced gastric cancer: anatomical drainage and clinical application

Lymph node metastases are an independent prognosis factor in gastric carcinoma (GC) patients.Radical lymphadenectomy can improve survival but it can also increase surgical morbidity.As a principle, sentinel node (SN) navigation surgery can avoid unnecessary lymphadenectomy without compromising prognosis.In this pilot study, 24 patients with untreat

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Leveraging Prior Concept Learning Improves Generalization From Few Examples in Computational Models of Human Object Recognition

Humans quickly and accurately learn new visual concepts from sparse data, sometimes just a single example.The impressive performance of artificial neural networks which hierarchically pool afferents across scales and positions suggests that the hierarchical organization of the human visual system is icon track bar f250 critical to its accuracy.Thes

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Innovative Feature Extraction and Machine Learning Joint Approaches for Automated Detection of Focal Cortical Dysplasia Type II

Focal cortical dysplasia type II (FCD II) is an epileptogenic lesion often associated with pharmacoresistant epilepsy.Yet, owing to their subtle appearance, identifying these lesions via 3D Magnetic Resonance Image (MRI) remains a complex challenge, rendering them susceptible to evasion by conventional visual analysis.In this study, we consider adv

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